Approved Jan 2026 · FDA label

Zepbound KwikPen: four doses in one pen

The Zepbound KwikPen is a pen holding four fixed weekly doses of one strength (2.5 to 15 mg), 0.6 mL each, in 2.4 mL. Each week you attach a new needle and prime it, and you throw it away after 4 doses or 30 days.

Tirzepatide Calculator editorial teamUpdated 5 sources

Single-patient useThe label: “Never share ZEPBOUND KwikPen between patients, even if the pen needle is changed.”[1] The KwikPen is also “not recommended for self-administration by those who are visually impaired.”[1]

Zepbound KwikPen strengths and price

The FDA added the KwikPen to the Zepbound and Mounjaro labels on January 20, 2026.[2][5] Each pen holds 2.4 mL and delivers four doses of 0.6 mL; it “contains additional volume to allow for device priming.”[1]

Zepbound KwikPen strengths
Dose per injectionDoses per penTotal per penSelf-pay per pen*
2.5 mg / 0.6 mL410 mg / 2.4 mL$299
5 mg / 0.6 mL420 mg / 2.4 mL$399
7.5 mg / 0.6 mL430 mg / 2.4 mL$449 (regular $499)
10 mg / 0.6 mL440 mg / 2.4 mL$449 (regular $699)
12.5 mg / 0.6 mL450 mg / 2.4 mL$449 (regular $699)
15 mg / 0.6 mL460 mg / 2.4 mL$449 (regular $699)

* LillyDirect self-pay, checked November 13, 2026; the KwikPen is priced the same as four single-dose vials. Lower prices for 7.5 mg and up apply on the first fill and on refills within 45 days. LillyDirect also lists “Select insurance accepted” for the KwikPen.[4] Lilly announced the U.S. launch on February 23, 2026.[3]

What the Instructions for Use say

The KwikPen instructions come down to five rules: four doses, prime weekly, ignore the clicks, no fifth dose, and no syringes.

  • “Each pen contains 4 fixed doses, one dose taken weekly.”[1]
  • “Prime before each weekly injection.” A new pen needle is needed for each weekly injection; needles are bought separately.[1][4]
  • “Do not count clicks as you select the dose.”[1]
  • “The Pen will prevent you from dialing a full dose after you have given yourself 4 weekly doses.”[1]
  • “Do not transfer ZEPBOUND from your Pen into a syringe.”[1]

This is a summary. Follow the Instructions for Use packed with the pen, which have drawings of each step. Why taking partial doses from the pen is not part of the label is covered on microdosing tirzepatide.

Storage

Once opened, a KwikPen is thrown away after 30 days or 4 doses, whichever comes first.[1]

KwikPen storage from the label
SituationWhat the label says
UnopenedRefrigerate at 2–8 °C (36–46 °F) until the expiration date, or keep at up to 30 °C (86 °F) and throw away after 30 days
In useFridge or up to 30 °C
When to throw awayAfter a total of 30 days at room temperature, 30 days after first use, or after 4 weekly doses, whichever comes first, “even if there is medicine left in it”
AlwaysDo not freeze. Keep in the original carton to protect from light.

Storage source: Zepbound label and Instructions for Use.[1]

KwikPen vs single-dose pen

The KwikPen holds four 0.6 mL doses and needs a needle attached each week; the single-dose pen holds one 0.5 mL dose with a built-in needle.[1]

  • Doses: four per KwikPen, one per single-dose pen.
  • Volume per dose: 0.6 mL in the KwikPen (with preservatives benzyl alcohol and phenol) vs 0.5 mL in the preservative-free single-dose pen.[1]
  • Needle: attached by you each week vs built in.
  • Same doses and schedule. See all four presentations compared.

Frequently asked questions

How many doses are in a Zepbound KwikPen?

Four fixed weekly doses of one strength, 0.6 mL each.[1]

Can I get a fifth dose out of the KwikPen?

No. The extra liquid is for priming, and the pen prevents dialing a full dose after four doses. The label says to throw it away after 4 doses even if medicine is left.[1]

Should I count the clicks on the KwikPen?

No. The label says: “Do not count clicks as you select the dose.”[1]

Can I draw Zepbound out of the KwikPen with a syringe?

The label says not to: “Do not transfer ZEPBOUND from your Pen into a syringe.”[1]

Sources

  1. Zepbound (tirzepatide) injection: prescribing information, Medication Guide and Instructions for Use · Eli Lilly and Company, via NLM DailyMed, label effective August 28, 2026
  2. Zepbound supplement approval letter S-002 (KwikPen) · U.S. Food and Drug Administration, January 20, 2026
  3. Zepbound now available in multi-dose KwikPen · Eli Lilly and Company press release, February 23, 2026
  4. Zepbound on LillyDirect: formats and self-pay prices · Eli Lilly and Company, accessed November 13, 2026
  5. Mounjaro (tirzepatide) injection: prescribing information and Instructions for Use · Eli Lilly and Company, via NLM DailyMed, label effective August 27, 2026